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Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records
2016
Frontiers in Genetics
Autoimmune diseases represent a significant medical burden affecting up to 5-8% of the U.S. population. While genetics is known to play a role, studies of common autoimmune diseases are complicated by phenotype heterogeneity, limited sample sizes, and a single disease approach. Here we performed a targeted genetic association study for cases of multiple sclerosis (MS), rheumatoid arthritis (RA), and Crohn's disease (CD) to assess which common genetic variants contribute individually and
doi:10.3389/fgene.2016.00185
pmid:27812365
pmcid:PMC5071319
fatcat:o4pxlbf7xrbb3evbrqm7bpsdd4