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<b><i>Background:</i></b> Injectable glucagon-like peptide-1 receptor agonists (GLP-1RAs) are proven to be well tolerated and efficacious in people with type 2 diabetes mellitus (T2DM) fasting during Ramadan. The first oral GLP-1RA semaglutide, also indicated for the treatment of T2DM, has specific dosing instructions to optimize treatment exposure, which may need to be altered during Ramadan fasting to ensure optimal efficacy. <b><i>Summary:</i></b> Given the lack of current published evidencedoi:10.1159/000527475 fatcat:desaoq2c6jh7pcxtidhesoqkse