6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA

Muhammet Tanc, Fabrizio Carta, Andrea Scozzafava, Claudiu T. Supuran
2015 Organic and biomolecular chemistry  
A series of 6-substituted 2-benzoxathiine-2,2-dioxides were synthesized starting from 2,5-dihydroxybenzaldehyde, and then screened in vitro for their inhibition properties against five human carbonic anhydrase (hCA, EC isoforms.
doi:10.1039/c4ob02155j pmid:25373598 fatcat:ia2h54qgjvexvgxfhbgayiotcq