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6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA
2015
Organic and biomolecular chemistry
Preserved Fulltext
A series of 6-substituted 2-benzoxathiine-2,2-dioxides were synthesized starting from 2,5-dihydroxybenzaldehyde, and then screened in vitro for their inhibition properties against five human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms.
doi:10.1039/c4ob02155j
pmid:25373598
fatcat:ia2h54qgjvexvgxfhbgayiotcq