Covariant Image Representation with Applications to Classification Problems in Medical Imaging

Dohyung Seo, Jeffrey Ho, Baba C. Vemuri
<span title="2015-07-25">2015</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="" style="color: black;">International Journal of Computer Vision</a> </i> &nbsp;
Images are often considered as functions defined on the image domains, and as functions, their (intensity) values are usually considered to be invariant under the image domain transforms. This functional viewpoint is both influential and prevalent, and it provides the justification for comparing images using functional L p -norms. However, with the advent of more advanced sensing technologies and data processing methods, the definition and the variety of images has been broadened considerably,
more &raquo; ... nd the long-cherished functional paradigm for images is becoming inadequate and insufficient. In this paper, we introduce the formal notion of covariant images and study two types of covariant images that are important in medical image analysis, symmetric positive-definite tensor fields and Gaussian mixture fields, images whose sample values covary i.e., jointly vary with image domain transforms rather than being invariant to them. We propose a novel similarity measure between a pair of covariant images considered as embedded shapes (manifolds) in the ambient space, a Cartesian product of the image and its sample-value domains. The similarity measure is based on matching the two embedded low-dimensional shapes, and both the extrinsic geometry of the ambient space and the intrinsic geometry of the shapes are incorporated in computing the similarity measure. Using this similarity as an affinity measure in a supervised learning framework, we demonstrate its effectiveness on two challenging classification problems: classification of brain MR images based on patients' age and (Alzheimer's) disease status and seizure detection from high angular resolution diffusion magnetic resonance scans of rat brains.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="">doi:10.1007/s11263-015-0841-x</a> <a target="_blank" rel="external noopener" href="">pmid:27182122</a> <a target="_blank" rel="external noopener" href="">pmcid:PMC4863719</a> <a target="_blank" rel="external noopener" href="">fatcat:fhb4putb5netfi3tv6doc5yb4e</a> </span>
<a target="_blank" rel="noopener" href=";blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href=""> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> </button> </a> <a target="_blank" rel="external noopener" href="" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> </button> </a>