Random Forest as a Tumour Genetic Marker Extractor [article]

Raquel Pérez-Arnal, Dario Garcia-Gasulla, David Torrents, Ferran Parés, Ulises Cortés, Jesús Labarta, Eduard Ayguadé
2019 arXiv   pre-print
Finding tumour genetic markers is essential to biomedicine due to their relevance for cancer detection and therapy development. In this paper, we explore a recently released dataset of chromosome rearrangements in 2,586 cancer patients, where different sorts of alterations have been detected. Using a Random Forest classifier, we evaluate the relevance of several features (some directly available in the original data, some engineered by us) related to chromosome rearrangements. This evaluation
more » ... sults in a set of potential tumour genetic markers, some of which are validated in the bibliography, while others are potentially novel.
arXiv:1911.11471v1 fatcat:ebiztkufx5hvnpedj4yztibx4q