A simple one-pot synthesis of tert-butyldimethylsilyl-protected cyanohydrins

RYUJI YONEDA, HIDEKI HISAKAWA, SHINYA HARUSAWA, TAKUSHI KURIHARA
1987 Chemical and pharmaceutical bulletin  
A direct conversion of a variety of aldehydes to the corresponding tert-butyldimethylsilyl protected cyanohydrins is described, by using tert-butyldimethylsilyl chloride and lithium cyanide.
doi:10.1248/cpb.35.3850 fatcat:pc6ddg7fmbarjoktflgaqv2q7a