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Suitability of different mapping algorithms for genome-wide polymorphism scans with Pool-Seq data
[article]
2016
bioRxiv
pre-print
The cost-effectiveness of sequencing pools of individuals (Pool-Seq) provides the basis for the popularity and wide-spread use of this method for many research questions, ranging from unravelling the genetic basis of complex traits to the clonal evolution of cancer cells. Because the accuracy of Pool-Seq could be affected by many potential sources of error, several studies determined, for example, the influence of the sequencing technology, the library preparation protocol, and mapping
doi:10.1101/052845
fatcat:ppdy2c4euva6jiogpg732buou4