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Enantioselective synthesis of (+)-Sedridine, (-)-Allosedridine and their N-Methyl analogs via Maruoka-Keck allylation and CBS reduction
2022
figshare.com
A simple synthetic approach has been developed for the enantioselective total synthesis of (+)-Sedridine, (-)-Allosedridine and their analogs such as (+)-N- Methyl Sedridine and (-)-N-Methylallosedridine. The synthesis was achieved by using commercially available starting materials via Maruoka-Keck allylation, Wacker oxidation, and CBS reduction. The synthetic root provides a good diastereomeric ratio and high yields.
doi:10.6084/m9.figshare.19932128.v1
fatcat:nrj4a5e2o5d6xkijz2ydomxid4