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Microorganisms commonly produce many high-demand industrial products like fuels, food, vitamins, and other chemicals. Microbial strains are the strains of microorganisms, which can be optimized to improve their technological properties through metabolic engineering. Metabolic engineering is the process of overcoming cellular regulation in order to achieve a desired product or to generate a new product that the host cells do not usually need to produce. The prediction of genetic manipulationsdoi:10.1515/jib-2020-0037 pmid:34348418 pmcid:PMC8573224 fatcat:unp4frm6o5bojcg47ilhkublpi