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No expression of porcine endogenous retrovirus after pig to monkey xenotransplantation
2014
Laboratory Animal Research
Preserved Fulltext
This study was performed to investigate the expression of two porcine endogenous retrovirus (PERV) elements, PERV gag and full-length conserved PERV, in blood cells collected periodically from organrecipient monkeys that underwent pig to non-human primate xenotransplantation. The heart and kidney-respectively acquired from α-1,3-galactosyltransferase knockout (GT-KO) pigs that survived for24 and 25 days-were xenografted into cynomolgus monkeys. The two PERV elements expressed in the xenografted
doi:10.5625/lar.2014.30.2.90
pmid:24999364
pmcid:PMC4079837
fatcat:hnrwzzqojvb5vojra7lav4jneq