Imaging of Osteoarthritis

Ali Guermazi, Daichi Hayashi, Felix Eckstein, David J. Hunter, Jeff Duryea, Frank W. Roemer
2013 Rheumatic Disease Clinics of North America  
Key Points: 1. Although conventional radiography is still the most commonly used imaging modality for clinical management of osteoarthritis patients, and loss of joint space width represents the only FDA-approved endpoint for structural disease progression in clinical trials, MR imaging-based studies have revealed some of the limitations of radiography. 2. The ability of MR to image the knee as a whole organ and to directly and three-dimensionally assess cartilage morphology and composition
more » ... s a crucial role in understanding the natural history of the disease and in the search for new therapies. 3. MR imaging of osteoarthritis can be classified into the following approaches: semiquantitative, quantitative, and compositional. 4. Ultrasound can also be useful to evaluate synovial pathology in osteoarthritis, particularly in the hand.
doi:10.1016/j.rdc.2012.10.003 pmid:23312411 fatcat:k336eiuwpjdspjcxh3lyhw6c3y