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Anti-stress Activity of Mitragyna africanus (Willd), Stembark Extract
2001
Journal of Medical Sciences
Preserved Fulltext
The acute toxicity and the effect of Mitragyna africanus stembark extract of methanol (CH OH) on stress were investigated in rats, using its effect o n 3 pentyleneterazole induced convulsions and its muscle relaxant effect. The extract did not produce any death in the treated rats even at the highest dose (6400mg kg ) used. It did not protect rats treated with convulsive doses of -1 pentylenetetrazol (100mg kg ) but increased the period of onset of convulsions -1 and decreased the number of
doi:10.3923/jms.2001.105.107
fatcat:ygx2eih5svfslcmjh6hkvhhp7e