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Mechanistic modeling of the SARS-CoV-2 disease map
2021
BioData Mining
AbstractHere we present a web interface that implements a comprehensive mechanistic model of the SARS-CoV-2 disease map. In this framework, the detailed activity of the human signaling circuits related to the viral infection, covering from the entry and replication mechanisms to the downstream consequences as inflammation and antigenic response, can be inferred from gene expression experiments. Moreover, the effect of potential interventions, such as knock-downs, or drug effects (currently the
doi:10.1186/s13040-021-00234-1
pmid:33478554
fatcat:gz6hyhjzlfbq3oxekedbfzhjp4