The ERGOTM genome analysis and discovery system

R. Overbeek
2003 Nucleic Acids Research  
The ERGO TM ( ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling, genetics and peer-reviewed journals to achieve a comprehensive analysis of genes and genomes. Far beyond any conventional systems that facilitate functional assignments, ERGO combines patternbased analysis with comparative genomics by visualizing genes within the context of regulation, expression
more » ... ing, phylogenetic clusters, fusion events, networked cellular pathways and chromosomal neighborhoods of other functionally related genes. The result of this multifaceted approach is to provide an extensively curated database of the largest available integration of genomes, with a vast collection of reconstructed cellular pathways spanning all domains of life. Although access to ERGO is provided only under subscription, it is already widely used by the academic community. The current version of the system integrates 500 genomes from all domains of life in various levels of completion, 403 of which are available for subscription.
doi:10.1093/nar/gkg148 pmid:12519973 pmcid:PMC165577 fatcat:w77bcjopvjfvjow3ua7zpsn5ge