Cytologic Assessment of Peroperative Pleural Effusion and Prognosis in Lung Cancer Patients Who Underwent Resection

KATSUO USUDA, YASUKI SAITO, CHIAKI ENDO, SATOMI TAKAHASHI, KEIJI KANMA, MASAMI SATO, MOTOYASU SAGAWA, NORIYOSHI NAGAMOTO, SHIGEFUMI FUJIMURA, SHIN'ICHIRO OTA
1992 Tohoku journal of experimental medicine  
Twenty-five of 108 lung cancer patients who underwent resection had cytologically positive pleural effusions. The rate at which cancer cells were detected was not related to the amount of the effusion. Almost one third of patients with cancer cells in effusion were alive at the end of the third postoperative year, provided that the pleura itself was free of metastasis at the time of operation. Correlation of the cytologically positive rate of pleural effusion (Y) with the degree of pleural
more » ... ree of pleural metastasis (X,), the degree of pleural involvement (X2), or the degree of nodal involvement (X3) was analyzed using the Hayashi's quantification method type I. The multiple correlation coefficient was 0.843. Partial correlation coefficients of X1, X2i and X3 were 0.733, 0.446, and 0.653, respectively. Pleural metastasis had the strongest effect on the cytologically positive rate of pleural effusion. lung cancer ; peroperative pleural effusion ; cytology ; prognosis ; Hayashi's quantification method Pleural effusion is frequently detected at thoracotomy for lung cancer. Up to the present, considerable attention has been directed to a relatively large amount of preoperative pleural effusion (Brinkman 1959; Jarvi et al. 1972; Decker et al. 1978; Canto et al. 1985; Monte et al. 1987; Mountain 1987 Mountain , 1988 , while, to the author's knowledge, there has been no study on a relatively small amount of peroperative pleural effusion in association with lung cancer. In
doi:10.1620/tjem.167.219 pmid:1488743 fatcat:3t4tpn7ltjcf7e7twwme2h4m7u