A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit <a rel="external noopener" href="https://mdpi-res.com/d_attachment/biomolecules/biomolecules-11-01245/article_deploy/biomolecules-11-01245.pdf">the original URL</a>. The file type is <code>application/pdf</code>.
Biomolecule and Bioentity Interaction Databases in Systems Biology: A Comprehensive Review
<span title="2021-08-20">2021</span>
<i title="MDPI AG">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/clnmwghhxzd35jr6jihmkh3gju" style="color: black;">Biomolecules</a>
</i>
Preserved Fulltext
Technological advances in high-throughput techniques have resulted in tremendous growth of complex biological datasets providing evidence regarding various biomolecular interactions. To cope with this data flood, computational approaches, web services, and databases have been implemented to deal with issues such as data integration, visualization, exploration, organization, scalability, and complexity. Nevertheless, as the number of such sets increases, it is becoming more and more difficult
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/biom11081245">doi:10.3390/biom11081245</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34439912">pmid:34439912</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8391349/">pmcid:PMC8391349</a>
<a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/32aums2jtbc5vdcdknzfczajsy">fatcat:32aums2jtbc5vdcdknzfczajsy</a>
</span>
more »
... an end user to know what the scope and focus of each repository is and how redundant the information between them is. Several repositories have a more general scope, while others focus on specialized aspects, such as specific organisms or biological systems. Unfortunately, many of these databases are self-contained or poorly documented and maintained. For a clearer view, in this article we provide a comprehensive categorization, comparison and evaluation of such repositories for different bioentity interaction types. We discuss most of the publicly available services based on their content, sources of information, data representation methods, user-friendliness, scope and interconnectivity, and we comment on their strengths and weaknesses. We aim for this review to reach a broad readership varying from biomedical beginners to experts and serve as a reference article in the field of Network Biology.
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210909154522/https://mdpi-res.com/d_attachment/biomolecules/biomolecules-11-01245/article_deploy/biomolecules-11-01245.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext">
<button class="ui simple right pointing dropdown compact black labeled icon button serp-button">
<i class="icon ia-icon"></i>
Web Archive
[PDF]
<div class="menu fulltext-thumbnail">
<img src="https://blobs.fatcat.wiki/thumbnail/pdf/30/90/3090d0ffca1127dd7706a15abc54511d0e87d286.180px.jpg" alt="fulltext thumbnail" loading="lazy">
</div>
</button>
</a>
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/biom11081245">
<button class="ui left aligned compact blue labeled icon button serp-button">
<i class="unlock alternate icon" style="background-color: #fb971f;"></i>
mdpi.com
</button>
</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391349" title="pubmed link">
<button class="ui compact blue labeled icon button serp-button">
<i class="file alternate outline icon"></i>
pubmed.gov
</button>
</a>