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The simultaneous association of epithelial and lymphoid tumour of the digestive tract is extremely rare it is most often a collision tumor combining the synchronization of adenocarcinoma end B lymphoma. We report the observation of a 45-year-old patient without a history who was hospitalized for management of adenocarcinoma of the sub-cardial region stomach. The patient was benefited on chemotherapy according to FLOT protocol and then had a total gastrectomy and Roux-en-Y oesophagojejunostomydoi:10.5281/zenodo.4011692 fatcat:6q4f76dabnbp5nx5vkve7r3hom