Hypotension is the most important complication following spinal anesthesia for caesarian delivery, which can produce adverse maternal symptoms and neonatal acid-base effects. Prompt effective treatment is considered essential to prevent fetal academia. Ephedrine and phenylephrine are two drugs known to prevent the hypotension following spinal anesthesia. Aim & Objective: Comparative evaluation of effect of prophylactic infusion of phenylephrine and ephedrine as a vasopressor therapy in spinal

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... esthesia in patients undergoing caesarian section and their effect on neonatal outcome. Observation: ephedrine and phenylephrine both maintained systolic, diastolic and mean arterial pressure, but ephedrine group required more additional bolous than phenylephrine group (p value <0.001). Phenylephrine group had acceptable pH value and lower acidosis than ephedrine group (p value <0.05). Conclusion: prophylactic Phenylephrine in a dose of 15 mcg/min is more efficacious in Comparision to Ephedrine 1.5 mg/min in maintaining arterial blood pressure following spinal anesthesia for caesarian section and has less neonatal acidosis.