Comparison of prophylactic infusion of phenylephrine with ephedrine for prevention of hypotension in elective lower segment caesarian section under spinal anasthesia

Harekrishna Ray, Madhumita Biswal, Basanta Kumar Pradhan, Sujata Misra, Mangal Charan Murmu
2022 International Journal of Health Sciences  
Hypotension is the most important complication following spinal anesthesia for caesarian delivery, which can produce adverse maternal symptoms and neonatal acid-base effects. Prompt effective treatment is considered essential to prevent fetal academia. Ephedrine and phenylephrine are two drugs known to prevent the hypotension following spinal anesthesia. Aim & Objective: Comparative evaluation of effect of prophylactic infusion of phenylephrine and ephedrine as a vasopressor therapy in spinal
more » ... esthesia in patients undergoing caesarian section and their effect on neonatal outcome. Observation: ephedrine and phenylephrine both maintained systolic, diastolic and mean arterial pressure, but ephedrine group required more additional bolous than phenylephrine group (p value <0.001). Phenylephrine group had acceptable pH value and lower acidosis than ephedrine group (p value <0.05). Conclusion: prophylactic Phenylephrine in a dose of 15 mcg/min is more efficacious in Comparision to Ephedrine 1.5 mg/min in maintaining arterial blood pressure following spinal anesthesia for caesarian section and has less neonatal acidosis.
doi:10.53730/ijhs.v6ns1.5155 fatcat:3d43wmq6mbflroesgkz2jhhs2u