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The Effects of Lead and Selenium on Melanoma Induction
International Journal of Medical Students
Melanoma is a malignant skin cancer and is one of the most aggressive malignancies in humans. Heavy metals, including lead, are known to cause cellular toxicity and have been studied for their potentials to induce apoptosis in tumor cells. Since selenium is considered to act protectively in cases of lead poisoning, this study focused on the effects of sodium selenite and lead chloride, both alone and combined, on melanoma cell apoptosis. Methods: This study was carried out by doing cell culturedoi:10.5195/ijms.2015.122 fatcat:r6jrnn7tgvfktozr6pyshbloty