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Characterization of the rhp7+ and rhp16+ genes in Schizosaccharomyces pombe
1999
Nucleic Acids Research
The global genome repair (GGR) subpathway of nucleotide excision repair (NER) is capable of removing lesions throughout the genome. In Saccharomyces cerevisiae the RAD7 and RAD16 genes are essential for GGR. Here we identify rhp7 + , the RAD7 homolog in Schizosaccharomyces pombe. Surprisingly, rhp7 + and the previously cloned rhp16 + are located very close together and are transcribed in opposite directions. Upon UV irradiation both genes are induced, reaching a maximum level after 45-60 min.
doi:10.1093/nar/27.17.3410
pmid:10446227
pmcid:PMC148581
fatcat:q72wruxnn5ha5ehrwjzfahrsa4