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Objective: this study aims to describe the epidemiological characteristics of yellow fever in Brazil in the period 2000-2012. Methods: this is a descriptive ecological epidemiological study, using information from Ministry of Health databases. Results: 326 cases of yellow fever were confirmed in Brazil during this period, with 156 deaths and an average case fatality rate of 47.8%; the young male adult age group was the most affected; in epizootic terms, 2,856 suspected cases of yellow fever indoi:10.5123/s1679-49742016000100002 pmid:27861674 fatcat:ly4em32epvgwtouyoaccfzqwqi