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A Deferasirox Derivative That Acts as a Multifaceted Platform for the Detection and Quantification of Fe3+
2021
Chemosensors
Here, we report that ExSO3H, a synthetically accessible, water-soluble, non-toxic derivative of the clinical iron chelator deferasirox, acts as a colorimetric chemosensor that permits the detection and quantification of Fe3+ in aqueous samples at pH 2–5. In addition, we observed that a fluorescent turn-on response was produced when this chelator was allowed to interact with human serum albumin (HSA). This fluorescence was quenched in the presence of Fe3+, thus allowing us to monitor the
doi:10.3390/chemosensors9040068
doaj:70c03152a38e43829d4ea61007b259b5
fatcat:5ebzgr6rufd4hfrtsfzilirfca