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Relationship of Octanoylcarnitine Concentrations to Age at Sampling in Unaffected Newborns Screened for Medium-Chain Acyl-CoA Dehydrogenase Deficiency
on behalf of the UK Collaborative Study of Newborn Screening for MCADD BACKGROUND: Although octanoylcarnitine (C8) concentrations measured from newborn screening dried blood spots are used to identify those at high risk of medium-chain acyl-CoA dehydrogenase deficiency (MCADD), age-related reference values are currently not available for unaffected newborn populations. Because age at sampling may vary within and between screening programs, variations in C8 concentrations by age may affectdoi:10.1373/clinchem.2010.143891 pmid:20413428 fatcat:pv6fqsbl7jgtbnetmgarggkcj4