Collagen and Use Its in the Treatment of Wounds

Anton Petrovich Ostroushko, Alexander Alexeyevich Andreev, Anastasiya Yurievna Laptiyova, Alexander Anatolievich Glukhov
2021 Vestnik of Experimental and Clinical Surgery  
Wounds take the main places of among surgical diseases, and the problem of developing new methods of their treatment remains relevant today. In recent years, the use of collagen has been widely used in the treatment of wounds. Collagen modulates the flow of fluid from the wound, facilitates the migration of fibroblasts and the formation of microvessels, helps in the synthesis of neodermal collagen matrices, forms complexes with biologically active substances and minimizes the formation of
more » ... formation of scars.Currently, collagen is used in the treatment of soft tissue wounds in the form of several pharmaceutical forms. Collagen sponges are used in the treatment of thermal and mechanical wounds, for local delivery of medicines. Collagen gels can be used for injections. Collagen can also be implemented in the form of a collagen shield. There are also collagen granules that have been developed for various compounds.Thus, the use of collagen is promising in the development of new medicinal preparation. However, for a wider disclosure of its clinical potential, it is necessary to thoroughly study all types of collagen and reveal their role at different stages of soft tissue repair.
doi:10.18499/2070-478x-2021-14-1-85-90 fatcat:kwbw3ew22jbszgqlgr76npxol4