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Microscopic Optical Projection Tomography In Vivo
2011
PLoS ONE
We describe a versatile optical projection tomography system for rapid three-dimensional imaging of microscopic specimens in vivo. Our tomographic setup eliminates the in xy and z strongly asymmetric resolution, resulting from optical sectioning in conventional confocal microscopy. It allows for robust, high resolution fluorescence as well as absorption imaging of live transparent invertebrate animals such as C. elegans. This system offers considerable advantages over currently available
doi:10.1371/journal.pone.0018963
pmid:21559481
pmcid:PMC3084718
fatcat:7f4sp7slw5bebicjz4xxctypuq