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Quantifying cerebral blood arrival times using hypoxia-mediated arterial BOLD contrast
[article]
2022
bioRxiv
pre-print
ABSTRACTCerebral blood arrival and tissue transit times are sensitive measures of the efficiency of tissue perfusion and can provide clinically meaningful information on collateral blood flow status. We exploit the arterial blood oxygen level dependent (BOLD) signal contrast established by precisely modulating arterial hemoglobin saturation using hypoxic respiratory challenges (dOHb-BOLD) to quantify arterial blood arrival times throughout the brain. A combination of hemodynamic lag with a
doi:10.1101/2022.03.27.485933
fatcat:ykdst5advfbqhmjblzqddurb2m