Dermatofibrosarcoma protuberans (DFSP) is an intermediate-grade tumor originating from the dermal fibroblasts. It's a locally invasive tumor with a potential of distant site metastasis. It usually forms after a long plaque which can be in an atrophic or a kleoid-like sclerotic character. The lesion very rarely settles in the breast. Here we report a 52 year-old Caucasian woman with a dermatofibrosarcoma protuberans in her right breast. Patient's lesion arose from a long time keloid-like

more »

... rophic looking plaque. Histopathologic examination did not reveal any malignant cells in the sclerotic plaque where the nodule arose from. Cells from nodular part of the lesion were CD34 positive immunohistohemically but there was no positive staining in the sclerotic plaque. The lesion was excised together with the pectoralis fascia. For reconstruction, an elliptically shaped latissimus dorsi musculocutaneous flap was designed. There were no recurrences in the postoperative 2nd year follow-up. To our knowledge this is the first reported case of dermatofibrosarcoma protuberans of a breast arising from a benign keloidlike sclerotic plaque. J Turk Acad Dermatol 2015; 9 (1): 1591c3.