Narrow escape and narrow capture problems which describe the average times required to stop the motion of a randomly travelling particle within a domain have applications in various areas of science. While for general domains, it is known how the escape time decreases with the increase of the trap sizes, for some specific 2D and 3D domains, higher-order asymptotic formulas have been established, providing the dependence of the escape time on the sizes and locations of the traps. Such results

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... ow the use of global optimization to seek trap arrangements that minimize average escape times. In a recent paper , an explicit size- and trap location-dependent expansion of the average mean first passage time (MFPT) in a 2D elliptic domain was derived. The goal of this work is to systematically seek global minima of MFPT for 1≤ N≤ 50 traps in elliptic domains using global optimization techniques, and compare the corresponding putative optimal trap arrangements for different values of the domain eccentricity. Further, an asymptotic formula the for the average MFPT in elliptic domains with N circular traps of arbitrary sizes is derived, and sample optimal configurations involving non-equal traps are computed.