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Urine metabolome of tuberculosis patients receiving intensive phase of treatment show diurnal variations
Diurnal variation in biofluid metabolome as observed in a healthy human may alter in perturbed conditions. Biofluids like urine are rich in molecular constituents including metabolites, and infectious disease conditions like tuberculosis (TB) may influence diurnal differences for which limited reports are available in the literature. In this study, we present an optimized gas chromatography coupled to a quadrupole mass spectrometry (GC-MS) method to analyze processed and trimethylsilyl (TMS)doi:10.1101/2021.03.30.21254606 fatcat:qiwr5p4b6fdkvny3uyfo4c6jtm