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A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research
The lymphatic vascular system plays an active role in immune cell trafficking, inflammation and cancer spread. In order to provide an in vivo tool to improve our understanding of lymphatic vessel function in physiological and pathological conditions, we generated and characterized a tdTomato reporter mouse and crossed it with a mouse line expressing Cre recombinase under the control of the lymphatic specific promoter Prox1 in an inducible fashion. We found that the tdTomato fluorescent signaldoi:10.7892/boris.147233 fatcat:u2d4vzhfcvalrcitareddwadmq