Endovascular Use of Cyanoacrylate-Lipiodol Mixture for Peripheral Embolization: Properties, Techniques, Pitfalls, and Applications

Pierre-Olivier Comby, Kévin Guillen, Olivier Chevallier, Marc Lenfant, Julie Pellegrinelli, Nicolas Falvo, Marco Midulla, Romaric Loffroy
2021 Journal of Clinical Medicine  
Endovascular embolization agents are particles and fluids that can be released into the bloodstream through a catheter to mechanically and/or biologically occlude a target vessel, either temporarily or permanently. Vascular embolization agents are available as solids, liquids, and suspensions. Although liquid adhesives (glues) have been used as embolic agents for decades, experience with them for peripheral applications is generally limited. Cyanoacrylates are the main liquid adhesives used for
more » ... endovascular interventions and have a major role in managing vascular abnormalities, bleeding, and many vascular diseases. They can only be injected as a mixture with ethiodized oil, which provides radiopacity and modulates the polymerization rate. This review describes the characteristics, properties, mechanisms of action, modalities of use, and indications of the cyanoacrylate-Lipiodol® combination for peripheral embolization.
doi:10.3390/jcm10194320 pmid:34640339 fatcat:d5pxl2hy2jfabczoxaic2qrcz4