A Comparison Between the American Diabetes Association Criteria and World Health Organization Criteria in the Diagnosis of Glucose Intolerance

Muhammet Güven, Mustafa Çetin, Kürflad Ünlüh›zarc›, Fahri Bayram, Fahrettin Kelefltimur
2000 Turkish Journal of Endocrinology and Metabolism   unpublished
The American Diabetes Association (ADA) published new diagnostic criteria and changed the fasting plasma glucose (FPG) diagnostic cut point from 140 mg/dl to 126 mg/dl for diabetes in 1997. This study was designed to compare the ADA criteria with the WHO criteria. We had performed an epidemiological study in 1994 on 1452 subjects. We could not obtain the records of four subjects and reviewed the records of 1448 subjects retrospectively. Forty seven (3.2%) versus 41 (2.8%) subjects were
more » ... jects were diagnosed with diabetes using the ADA and the WHO criteria, respectively. If FPG levels are considered as the main means of diagnosis and the cut point is reduced from 140 to 126 mg/dl the prevalence of diabetes is 2.5%, and 11 cases (0.7%) not have a diagnosis of diabetes. Of the 132 (9.1%) subjects diagnosed with glucose intolerance (IGT) according to the WHO criteria, 128 (8.8%) have IGT and 4 (0.3%) have diabetes according to the ADA criteria. Of the 1217 (84%) subjects with normal glucose tolerance (NGT) according to the WHO criteria, 1191 (82.2%) have NGT, 24 (1.7%) impaired fasting glucose (IFG), and 2 (0.1%) diabetes according to the ADA criteria. The present study showed that FPG level as a predictor of developing diabetes was important. In addition, we consider that 2-h plasma glucose (PG) level assessments must be performed.