Malignant B Cells From Patients With Primary Central Nervous System Lymphoma Express Stromal Cell-Derived Factor-1

Justine Smith, Katherine Falkenhagen, Sarah Coupland, Timothy Chipps, James Rosenbaum, Rita Braziel
2007 American Journal of Clinical Pathology  
A b s t r a c t Although the pathogenesis of primary central nervous system lymphoma (PCNSL) remains unclear, it is hypothesized that specific chemokine-chemokine receptor interactions may attract malignant B lymphocytes into the CNS. Formalin-fixed, paraffinembedded brain biopsy specimens from 40 patients with PCNSL were immunostained by an indirect immunohistochemical method incorporating antigen retrieval to detect the presence
doi:10.1309/utw7-2244-8442-4113 pmid:17369141 fatcat:ju46euts2nhwhahum6knerbfeu