Automatic quantification of microtubule dynamics

S. Hadjidemetriou, J.S. Duncan, D. Toomre, D. Tuck
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (IEEE Cat No. 04EX821)  
The dynamics of the microtubule assembly are significant both for the study of cell function and structure. Abnormal function of the assembly is involved in neurodegenerative diseases and cancer. Currently, microtubule dynamics are typically analyzed manually. We present an algorithm that quantifies the microtubule dynamics automatically. Thus, it allows a more extensive understanding of the assembly. We examine the sensitivity of the algorithm using phantom as well as real microscopic image data.
more » ... icroscopic image data.
doi:10.1109/isbi.2004.1398623 fatcat:4irwiuicnnbq7l6wfz3mkvl55u