Carbon Dioxide Exchange via the Mucosa in Healthy Middle Ear

Fumio Ikarashi, Sugata Takahashi, Yutaka Yamamoto
1999 Archives of Otolaryngology - Head and Neck Surgery  
Recent studies have shown that gas exchange via the middle ear mucosa, which is performed between the middle ear cleft and capillaries in the submucosal connective tissue, has an essential role in ventilation and pressure regulation in the middle ear cleft. We speculated that gas exchange via the mucosa is induced by the gas diffusion caused by the partial pressure gradient of gas between the middle ear cleft and submucosal capillaries. Objective: To evaluate the capacity of the gas exchange
more » ... the mucosa in the healthy middle ear of humans by examining the effect of the respiratory mode on middle ear pressure. Subjects and Methods: We selected 13 volunteers ranging in age from 25 to 44 years with healthy ear drums and type A tympanograms. Middle ear pressure was measured in 1 ear of each subject every 2 minutes using tympanometry while the respiratory mode was altered, with
doi:10.1001/archotol.125.9.975 pmid:10488982 fatcat:oi5bdtelmvfxnez7ijk6f6i6xu