Partition Coefficients of Polyphenols for Phosphatidylcholine Investigated by HPLC with an Immobilized Artificial Membrane Column

Yoshinori UEKUSA, Yuko TAKESHITA, Takeshi ISHII, Tsutomu NAKAYAMA
2008 Bioscience, biotechnology and biochemistry  
The biological activity of polyphenols in vitro reflects their affinity for cell membranes and the amount of cellular incorporation. The interaction of polyphenols with phosphatidylcholine was investigated by HPLC with an immobilized artificial membrane (IAM) column. The IAM partition coefficients (K IAM ) of the polyphenols, calculated by retention times, correlated well with the amounts of polyphenols incorporation into the liposomes.
doi:10.1271/bbb.80435 pmid:19060387 fatcat:hnk3bhtjm5h2jjdsssxbo5k4vy