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The classification of melanoma into four histological subtypes has been questioned regarding its clinical validity in providing relevant information for treatment for metastatic tumors. Specific genetic alterations are associated with particular clinical and histopathological features, suggesting that these could be helpful in refining existing melanoma classification schemes. We analyzed BRAF V600E mutated melanomas to explore the Reflectance confocal microscopy (RCM) utility as a screeningdoi:10.1371/journal.pone.0179745 pmid:28662062 pmcid:PMC5491027 fatcat:ztkvcxdo6ncuplgwqydp52y4wu