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Simple HPLC Method for the Determination of Caspofungin in Human Plasma
Clinical Pharmacology & Biopharmaceutics
Antifungal caspofungin (CPFG) was approved for the treatment of febrile neutropenia (FN) as the empiric treatment. However, the relationship between pharmacokinetic properties of CPFG and its clinical effects in patients with FN has not been fully established yet. Thus, in the present study, we tried to establish the simple and quantitative HPLC method to measure CPFG in human plasma with liquid-liquid extraction. CPFG in human plasma was extracted by liquid-liquid extraction and was separateddoi:10.4172/2167-065x.1000137 fatcat:xexmtmav6rgpja725rktjr3qla