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A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation
2020
Proceedings of the National Academy of Sciences of the United States of America
Proper resolution of inflammation is vital for repair and restoration of homeostasis after tissue damage, and its dysregulation underlies various noncommunicable diseases, such as cardiovascular and metabolic diseases. Macrophages play diverse roles throughout initial inflammation, its resolution, and tissue repair. Differential metabolic reprogramming is reportedly required for induction and support of the various macrophage activation states. Here we show that a long noncoding RNA (lncRNA),
doi:10.1073/pnas.2005924117
pmid:32513690
fatcat:wgmp3us4vfd4bbxozcwhfgsqcq