This work is concerned with a comparative study of performances of meshfree (radial basis functions) and mesh-based (finite difference) schemes in terms of their accuracy and computational efficiency while solving multi-dimensional initial-boundary value problems governed by a nonlinear time-dependent reaction-diffusion Brusselator system. For computing the approximate solution of the Brusselator system, we use linearly implicit Crank-Nicolson (LICN) scheme, Peaceman-Rachford alternating

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... on implicit (ADI) scheme and exponential time differencing locally one dimensional (ETD-LOD) scheme as mesh-based schemes and multiquadric radial basis function (MQRBF) as a meshfree scheme. A few numerical results are reported.