Understanding the spatiotemporal distributions and variation characteristics of water quality parameters is crucial for ecosystem restoration and management of lakes, in particular, Lake Qilu (QL), a typical plateau shallow lake on the Yunnan-Guizhou Plateau, southwestern China. To identify the main causes of harmful algal blooming and continuous water quality decline, the total phosphorus (TP), total nitrogen (TN), water temperature (WT), dissolved oxygen (DO), chlorophyll-a (Chl-a), pH, and

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... rbidity in hypereutrophic Lake Qilu from January 2017 to December 2021 were analyzed. The results showed a complex pattern in spatiotemporal distribution and variation. WT showed no significant change in the vertical profile. DO and pH value variations were caused by both physical and biochemical processes, especially at the bottom of Lake QL with an anaerobic environment. The Trophic State Index (TSI) assessment results showed that Lake QL is a eutrophic (70.14% of all samples, 50 < TSI < 70) to a hypereutrophic lake (29.86%, 70 < TSI) with poor water quality (WQI < 25). TP and WT were the main factors controlling harmful algal blooms (HABs) based on the statistical analysis of Principal Component Analysis (PCA), Random Forest Model (RFM), and Correlation Analysis (CA). In lake QL, TP loading reduction and water level increase might be the key strategies for treating HABs in the future. Based on our results, reducing TP loading may be more effective than reducing TN to prevent HABs in the highly eutrophicated Lake Qilu.