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Influence of network topology and data collection on network inference
2003
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
We recently developed an approach for testing the accuracy of network inference algorithms by applying them to biologically realistic simulations with known network topology. Here, we seek to determine the degree to which the network topology and data sampling regime influence the ability of our Bayesian network inference algorithm, NETWORKINFERENCE, to recover gene regulatory networks. NETWORKINFERENCE performed well at recovering feedback loops and multiple targets of a regulator with small
pmid:12603026
fatcat:oiizxsdu2re3jpnvghswwn6tya