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In silico pathway analysis and tissue specific cis-eQTL for colorectal cancer GWAS risk variants
2017
BMC Genomics
Genome-wide association studies have identified 55 genetic variants associated with colorectal cancer risk to date. However, potential causal genes and pathways regulated by these risk variants remain to be characterized. Therefore, we performed gene ontology enrichment and pathway analyses to determine if there was an enrichment of genes in proximity to the colorectal cancer risk variants that could further elucidate the probable causal genes and pathways involved in colorectal cancer biology.
doi:10.1186/s12864-017-3750-2
pmid:28506205
pmcid:PMC5432975
fatcat:pvedgrmeu5gstpncekomyr327m