Dynamics of adrenocorticotropin after stimulation with metyrapone (DYNAMO)

Sebastian Noe, Werder Alexander von, Roman Iakoubov, Bruno Neu, Heike Schneider, Markus Thaler, Peter Luppa
2016 Endocrine Abstracts  
Patients from a tertiary endocrine center at a University Hospital in Munich, Germany, were tested using Metyrapone (Metopirone®, HRA Pharma, France), administered at a dose of 40 mg/kg bodyweight at 8 a.m. Levels of ACTH were determined at 0, 60, 120, 180, and 240 minutes. Patients were categorized according to their need of glucocorticoid substitution at the end of follow-up. The study was approved by the local Ethics Committee with a limitation to 25 patients.
doi:10.1530/endoabs.41.gp168 fatcat:5d7xo7hbfrghfjn363ssshsoy4