Flow Cytometry Bioinformatics

Kieran O'Neill, Nima Aghaeepour, Josef Špidlen, Ryan Brinkman, Shoshana Wodak
2013 PLoS Computational Biology  
Flow cytometry bioinformatics is the application of bioinformatics to flow cytometry data, which involves storing, retrieving, organizing, and analyzing flow cytometry data using extensive computational resources and tools. Flow cytometry bioinformatics requires extensive use of and contributes to the development of techniques from computational statistics and machine learning. Flow cytometry and related methods allow the quantification of multiple independent biomarkers on large numbers of
more » ... le cells. The rapid growth in the multidimensionality and throughput of flow cytometry data, particularly in the 2000s, has led to the creation of a variety of computational analysis methods, data standards, and public databases for the sharing of results.
doi:10.1371/journal.pcbi.1003365 pmid:24363631 pmcid:PMC3867282 fatcat:jp7cltm3kjcqxnupcxbgflnamm