The universal existence of tubby-like proteins (TLPs) both in animals and plants implies that TLPs may play key roles in basic biological processes. In rice genome there are 14 members of TLP genes. We examined the expression of TLPs in rice leaves at different developmental stages with TLP-specific antibodies. We also investigated the expression pattern of TLPs at different times in incompatible responses mediated by bacterial blight-resistant gene Xa21 against Xanthomonas oryzae pv. oryzae

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... o). We found that the expression of OsTLP2, 7, 8 and 9 varied in incompatible responses and that the expression patterns varied among compatible interaction, incompatible interaction and mock control. These results provide important clues for the interpretation of TLP function in rice, especially in the interaction between rice and Xoo.