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Guoji Yanke Zazhi
Microglial activation is one of the main pathogenic factors to cause retinal neuroinflammation. Recently, with the advancement of retinal imaging technologies, hyperreflective foci(HRF), as a novel biomarker in optical coherence tomography(OCT)imaging, have received more attention in retinal neuroinflammation. Current research demonstrated that HRF are the aggregates mainly derived from the activated microglia in retina or mononuclear phagocyte-macrophage from the blood. HRF were defined asdoi:10.3980/j.issn.1672-5123.2022.1.10 doaj:929c3c58f4fa4665b1f72bdf0f034689 fatcat:b4oggaarqrftfbzrg2ickrakvy