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An epigenetic map of malaria parasite development from host to vector
2020
Scientific Reports
The malaria parasite replicates asexually in the red blood cells of its vertebrate host employing epigenetic mechanisms to regulate gene expression in response to changes in its environment. We used chromatin immunoprecipitation followed by sequencing in conjunction with RNA sequencing to create an epigenomic and transcriptomic map of the developmental transition from asexual blood stages to male and female gametocytes and to ookinetes in the rodent malaria parasite Plasmodium berghei. Across
doi:10.1038/s41598-020-63121-5
pmid:32286373
fatcat:lze5xvi2nje67ptq53coof2pvm