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Genetic contribution and associated pathophysiology in end-stage renal disease
2010
The Application of Clinical Genetics
End-stage renal disease (ESRD) or chronic kidney disease (CKD) is the terminal state of the kidney when its function has been permanently and irreversibly damaged. A wide variety of etiologies and pathological processes culminate in ESRD, and both environmental and genetic factors contribute to its development and progression. Various reports suggest that susceptibility to develop ESRD has a significant genetic component. These studies include familial aggregation studies, comparisons of
pmid:23776353
pmcid:PMC3681165
fatcat:ehtcgrso6nd7bakxobekrfnvui