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Archaic adaptive introgression in TBX15/WARS2
[article]
2015
bioRxiv
pre-print
A recent study conducted the first genome-wide scan for selection in Inuit from Greenland using SNP chip data. Here, we report that selection in the region with the second most extreme signal of positive selection in Greenlandic Inuit favored a deeply divergent haplotype that is closely related to the sequence in the Denisovan genome, and was likely introgressed from an archaic population. The region contains two genes, WARS2 and TBX15, and has previously been associated with adipose tissue
doi:10.1101/033928
fatcat:gkt2r7qmfngl5gq5d67zbm4nxu